Standard methods misplace 33% of deep microbial branches when analyzing >1,000 genomes
The new algorithm reduces errors by 52% using statistical checks against "long-branch attraction" artifacts
Next step: Applying this to controversial Archaea-Eukarya divergence timing
Microbiologists can now trust evolutionary models for synthetic biology applications
The study analyzed 11.4 billion DNA base pairs across 3,072 genomes—the largest test of microbial phylogenetics to date.