A new imaging technique reveals how scramblase proteins transport lipids across cell membranes at the single-molecule level, offering clues to treat blood disorders and neurodegenerative diseases.

The method tracks single proteins at 100x higher resolution than previous techniques

Reveals scramblases transport lipids at rates up to 10,000 molecules per second

First step toward designing drugs to modulate scramblase activity

Could explain why some patients don't respond to blood thinners

Scramblases can flip lipid molecules 100,000 times faster than natural membrane diffusion—akin to a freight train outpacing a bicycle.

Scientists Capture First Real-Time Footage of Single Scramblase Proteins in Action